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Recombinant human GCH1 protein, C-His

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42069p-100ug
Product Name Recombinant human GCH1 protein, C-His
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human GCH1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1-250/250
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 2643
Swiss Prot P30793
Background GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.