Recombinant human DAGLB protein, N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42098P-100ug |
| Product Name | Recombinant human DAGLB protein, N-His |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human DAGLB protein is expressed in E.coli with N-His. It contains the amino acid sequence of 470-672 /672 |
| Storage Buffer | 20mM Tris-Hcl (pH=8.0) with 8M Urea |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 221955 |
| Swiss Prot | Q8NCG7 |
| Background | KCCR13L, is a 672 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. DAGL beta uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGL beta functions at an optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2, but not PMSF. There are three isoforms of DAGL beta that are produced as a result of alternative splicing events. |