IL-18 Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-42148R-Biotin-100uL |
| Product Name | IL-18 Polyclonal Antibody, Biotin Conjugated |
| Applications |
IHC-P
IHC-F
|
| Reactivity | Rat |
| Predicted Reactivity | Mouse |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | Recombinant rat IL-18 protein |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 29197 |
| Swiss Prot | P97636 |
| Synonyms | Interleukin-18; interferon gamma-inducing factor IGIF; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; Iboctadekin; IFN gamma inducing factor; IGIF; IL 1 gamma; IL 18; IL-18; IL 1g; IL1 gamma; IL18 protein; IL1F4; IL1g; IL1gamma; ILIF4; Interferon gamma inducing factor; Interleukin 1 gamma; Interleukin18; MGC12320; IL18_HUMAN; IL18_RAT; IL18_MOUSE. |
| Background | IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |
| Application Dilution | |
| IHC-P | =1:100-500 |
| IHC-F | IHC-F=1:400-800 |
Frequently asked questions
Which applications is IL-18 Polyclonal Antibody, Biotin Conjugated (bs-42148R-Biotin) validated for, and at what dilution?
bs-42148R-Biotin is validated for IHC-P (IHC-P=1:100-500); IHC-F (IHC-F=1:400-800). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does IL-18 Polyclonal Antibody, Biotin Conjugated (bs-42148R-Biotin) react with?
Tested reactivity: Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse.
How should bs-42148R-Biotin be stored?
Store at -20C for 12 months. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise IL-18 Polyclonal Antibody, Biotin Conjugated (bs-42148R-Biotin)?
Recombinant rat IL-18 protein