Recombinant human ADAMTS5 protein

Overview
Catalog #	bs-42150p-100ug
Product Name	Recombinant human ADAMTS5 protein
Applications	Others
Reactivity	Others
Specifications
Conjugation	Unconjugated
Source	Recombinant human ADAMTS5 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 739-930/930
Storage Buffer	0.01M TBS(pH7.4)
Storage Condition	The product should be stored at -70°C or -20°C.
Target
Gene ID	23794
Swiss Prot	Q9UNA0
Background	This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016]