Recombinant mouse IL18 protein, N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42154p-100ug |
| Product Name | Recombinant mouse IL18 protein, N-His |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant mouse IL18 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 36-192/192 |
| Storage Buffer | 20mM Tris-HCl (pH8.0) with 2M Urea. |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 16173 |
| Swiss Prot | P70380 |
| Background | IL18 (IFN-gamma-inducing factor, IGIF) is a novel pro-inflammatory cytokine that augments natural killer (NK) activity in spleen cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. |