| Overview |
| bs-42203P-APC-100ug |
| Recombinant mouse NALP3 protein, N-Trx-His, APC Conjugated |
| Others |
| Others |
| Specifications |
| APC |
| Recombinant mouse NALP3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-93/1033 |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target |
| Q8R4B8 |
| May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm. |
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