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Recombinant human LPL protein, N-His

Applications

  • Others

Reactivity

  • Others
Overview
Catalog # bs-42218p-100ug
Product Name Recombinant human LPL protein, N-His
Applications Others
Reactivity Others
Specifications
Conjugation Unconjugated
Source Recombinant human LPL protein is expressed in E.coli with N-His. It contains the amino acid sequence of 172-385/475
Storage Buffer 0.01M TBS(pH7.4)
Storage Condition The product should be stored at -70°C or -20°C.
Target
Gene ID 4023
Swiss Prot P06858
Background Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.