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RANK Polyclonal Antibody, AbBy Fluor-750 Conjugated

Applications

  • WB

Reactivity

  • Mouse

Predicted Reactivity

  • Rat
Overview
Catalog # bs-42227R-BF750-100uL
Product Name RANK Polyclonal Antibody, AbBy Fluor-750 Conjugated
Applications
WB
Reactivity Mouse
Predicted Reactivity Rat
Specifications
Conjugation AbBy Fluor-750
Host Rabbit
Source Recombinant mouse RANK protein
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 21934
Swiss Prot O35305
Subcellular location Cell membrane
Synonyms TNFRSF11A; CD265; CD265 antigen; Activator of NFKB; EOF; FEO; mRANK; NFKB activator; ODFR; OFE; Osteoclast differentiation factor receptor; PDB 2; Receptor activator of NF KB; receptor activator of nuclear factor kappa B; TNFRSF 11A; TNFSF11; TRANCE R; RANK receptor; TNR11_HUMAN.
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is RANK Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-42227R-BF750) validated for, and at what dilution?

bs-42227R-BF750 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does RANK Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-42227R-BF750) react with?

Tested reactivity: Mouse. Predicted reactivity (expected from sequence homology but not yet tested): Rat.

How should bs-42227R-BF750 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise RANK Polyclonal Antibody, AbBy Fluor-750 Conjugated (bs-42227R-BF750)?

Recombinant mouse RANK protein

What are the excitation and emission wavelengths of the AbBy Fluor-750 conjugate (bs-42227R-BF750)?

AbBy Fluor-750 on bs-42227R-BF750: excitation / emission 749nm/775nm.

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