Recombinant human TMEM106B protein, N-Trx-His, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-42250P-APC-100ug |
| Product Name | Recombinant human TMEM106B protein, N-Trx-His, APC Conjugated |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | APC |
| Source | Recombinant human TMEM106B protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 2-96/274 |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target | |
| Swiss Prot | Q9NUM4 |
| Background | TMEM106B is a 274 amino acid single-pass membrane protein that is encoded by a gene which maps to human chromosome 7. Chromosome 7 houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia. |