| Overview |
| bs-42280P-Biotin-100ug |
| Recombinant human PPARGC1A, N-Trx-His, Biotin Conjugated |
| Others |
| Others |
| Specifications |
| Biotin |
| Recombinant human PPARGC1A is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 11-280/798 |
| Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Target |
| Q9UBK2 |
| The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity (referenced from entrez gene. |
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