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KCNA3 Polyclonal Antibody, AbBy Fluor-488 Conjugated

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-42284R-BF488-100uL
Product Name KCNA3 Polyclonal Antibody, AbBy Fluor-488 Conjugated
Applications
WB
Reactivity Human
Specifications
Conjugation AbBy Fluor-488
Host Rabbit
Source Recombinant human KCNA3 protein
Modification Site Ser10
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 3738
Swiss Prot P22001
Subcellular location Cell membrane
Synonyms Potassium Channel Kv1.3; HGK 5; HGK5; HLK 3; HLK3; HPCN 3; HPCN3; HuKIII; KCNA 3; KV1.3; MK 3; MK3; PCN 3; PCN3; Potassium channel 3; Potassium voltage gated channel shaker related subfamily member 3; Potassium voltage gated channel subfamily A member 3; Type n potassium channel; Voltage gated potassium channel subunit Kv1.3.
Background Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. [provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-5000

Frequently asked questions

Which applications is KCNA3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-42284R-BF488) validated for, and at what dilution?

bs-42284R-BF488 is validated for WB (1:300-5000). These are recommended starting dilutions; optimal dilutions should be determined by the end user.

Which species does KCNA3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-42284R-BF488) react with?

Tested reactivity: Human.

How should bs-42284R-BF488 be stored?

Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

What immunogen was used to raise KCNA3 Polyclonal Antibody, AbBy Fluor-488 Conjugated (bs-42284R-BF488)?

Recombinant human KCNA3 protein

What are the excitation and emission wavelengths of the AbBy Fluor-488 conjugate (bs-42284R-BF488)?

AbBy Fluor-488 on bs-42284R-BF488: excitation / emission 499nm/519nm.