Glutamine synthetase Polyclonal Antibody, AbBy Fluor-350 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-42310R-BF350 |
| Product Name | Glutamine synthetase Polyclonal Antibody, AbBy Fluor-350 Conjugated |
| Applications |
WB
IF
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | AbBy Fluor-350 |
| Host | Rabbit |
| Source | Recombinant human Glutamine synthetase protein |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 2752 |
| Swiss Prot | P15104 |
| Subcellular location | Cytoplasm |
| Synonyms | GLUL; cell proliferation-inducing protein 59; GLNA; GLNA_HUMAN; GLNS; Glutamate ammonia ligase; Glutamate decarboxylase; Glutamate--ammonia ligase; glutamine synthase; GS; PIG 43; PIG 59; PIG43; PIG59; Proliferation inducing protein 43. |
| Background | Glutamine Synthetase catalyzes the conversion of ammonia and glutamate to glutamine. It is found in astrocytes as an octamer of identical 42 kDa subunits. The function of Glutamine Synthetase is the detoxification of brain ammonia. It also has an important role in the metabolic regulation of neurotransmitter glutamate. Because of the multiple functions and importance of Glutamine Synthetase in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of Glutamine Synthetase is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer's disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation. The level of expression of Glutamine Synthetase is increased during ischemia in vivo or hypoxia in culture. |
| Application Dilution | |
| WB | |
| IF | |
Frequently asked questions
Which applications is Glutamine synthetase Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-42310R-BF350) validated for, and at what dilution?
bs-42310R-BF350 is validated for WB, IF.
Which species does Glutamine synthetase Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-42310R-BF350) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-42310R-BF350 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Glutamine synthetase Polyclonal Antibody, AbBy Fluor-350 Conjugated (bs-42310R-BF350)?
Recombinant human Glutamine synthetase protein