Recombinant mouse CLEC12A protein,N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42413P-100ug |
| Product Name | Recombinant mouse CLEC12A protein,N-His |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant mouse CLEC12A protein is expressed in E.coli with N-His. It contains the amino acid sequence of 69-267/267 |
| Storage Buffer | 20mM Tris-Hcl (pH=8.0) with 8M Urea |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 160364 |
| Swiss Prot | Q5QGZ9 |
| Background | The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-12A (C-type lectin domain family 12, member A), also known as CLL1, MICL, CLL-1 or DCAL-2, is a 275 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Existing as multiple alternatively spliced isoforms that are expressed in neutrophils, eosinophils, monocytes and dendritic cells, CLEC-12A functions as a cell surface receptor that acts as a negative regulator of granulocyte and monocyte function and, via this activity, modulates signaling cascades. CLEC-12A is highly subject to post-translational glycosylation at its N-terminus and may also exist as a homodimer. |