Recombinant human ADAMTS5 protei, N-His
Applications
Reactivity
| Overview | |
| Catalog # | bs-42469p-100ug |
| Product Name | Recombinant human ADAMTS5 protei, N-His |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human ADAMTS5 protei in E.coli with N-His. It contains the amino acid sequence of 485-624/930 |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 11096 |
| Swiss Prot | Q9UNA0 |
| Background | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016] |