Recombinant human Apolipoprotein E protein, C-His (HEK293)
Applications
Reactivity
| Overview | |
| Catalog # | bs-43018p-100ug |
| Product Name | Recombinant human Apolipoprotein E protein, C-His (HEK293) |
| Applications |
ELISA
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant human Apolipoprotein E protein, C-His (HEK293) protein is expressed in HEK293 with C-His. It contains the amino acid sequence of 19-317/317. |
| Storage Buffer | 0.01M TBS(pH7.4) |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | 348 |
| Swiss Prot | P02649 |
| Background | Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. ApoE exists in three major isoforms; E2, E3, and E4, which differ from one another by a single amino-acid substitution. Compared with E3 and E4, E2 exhibits the lowest receptor binding affinity. Defects in ApoE are a cause of hyperlipoproteinemia type III due to increased plasma cholesterol and triglycerides levels which are the consequence of impaired clearance of chylomicron and VLDL remnants. |