Defensin beta 2 Polyclonal Antibody, APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-4307R-APC |
| Product Name | Defensin beta 2 Polyclonal Antibody, APC Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Human |
| Specifications | |
| Conjugation | APC |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human beta 2 Defensin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 1673 |
| Swiss Prot | O15263 |
| Subcellular location | Secreted |
| Synonyms | BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB12; Beta-defensin 4A; Beta-defensin 2; Defensin, beta 2; Skin-antimicrobial peptide 1; DEFB4A |
| Background | Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is Defensin beta 2 Polyclonal Antibody, APC Conjugated (bs-4307R-APC) validated for, and at what dilution?
bs-4307R-APC is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does Defensin beta 2 Polyclonal Antibody, APC Conjugated (bs-4307R-APC) react with?
Tested reactivity: Human.
How should bs-4307R-APC be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise Defensin beta 2 Polyclonal Antibody, APC Conjugated (bs-4307R-APC)?
KLH conjugated synthetic peptide derived from human beta 2 Defensin
What are the excitation and emission wavelengths of the APC conjugate (bs-4307R-APC)?
APC on bs-4307R-APC: excitation / emission 650nm/660nm.