| Overview |
| bs-43082P-APC-100ug |
| Recombinant human TSH Alpha/Beta Heterodimer protein, C-His (HEK293), APC Conjugated |
| Others |
| Others |
| Specifications |
| APC |
| Recombinant human TSH Alpha/Beta Heterodimer protein is expressed in HEK293 cell with C-His.It contains the amino acid sequence of 25-116/116 (Alpha chain) & 21-138/138 (Beta chain) |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target |
| P01215 (alpha chain) & P01222 (beta chain) |
| The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013] |
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