Recombinant human CEACAM5 protein, C-His (HEK293), Biotin Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-43141P-Biotin-100ug |
| Product Name | Recombinant human CEACAM5 protein, C-His (HEK293), Biotin Conjugated |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | Biotin |
| Source | Recombinant human CEACAM5 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 35-685/702 |
| Storage Buffer | Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Target | |
| Swiss Prot | P06731 |
| Background | CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. |
Frequently asked questions
How is Recombinant human CEACAM5 protein, C-His (HEK293), Biotin Conjugated (bs-43141P-Biotin) produced?
Recombinant human CEACAM5 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 35-685/702