Recombinant mouse CD40L protein (HEK293), APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-43184P-APC-100ug |
| Product Name | Recombinant mouse CD40L protein (HEK293), APC Conjugated |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | APC |
| Source | Recombinant mouse CD40L protein (HEK293) is expressed in HEK293 cell with N-His. It contains the amino acid sequence of 115-260/260 |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target | |
| Swiss Prot | P27548 |
| Background | CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes. |
Frequently asked questions
How is Recombinant mouse CD40L protein (HEK293), APC Conjugated (bs-43184P-APC) produced?
Recombinant mouse CD40L protein (HEK293) is expressed in HEK293 cell with N-His. It contains the amino acid sequence of 115-260/260
What are the excitation and emission wavelengths of the APC conjugate (bs-43184P-APC)?
APC on bs-43184P-APC: excitation / emission 650nm/660nm.