Recombinant mouse CD80 protein, C-His (HEK293), APC Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-43640P-APC-100ug |
| Product Name | Recombinant mouse CD80 protein, C-His (HEK293), APC Conjugated |
| Applications |
OTHERS
|
| Reactivity | Others |
| Specifications | |
| Conjugation | APC |
| Source | Recombinant mouse CD80 protein is expressed in HEK293 cell with C-His. It contains the amino acid sequence of 37-245/306 |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Target | |
| Swiss Prot | Q00609 |
| Background | CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. |