| Overview |
| bs-4559R-HRP |
| alpha Adducin Polyclonal Antibody, HRP Conjugated |
| ELISA, IHC-P, IHC-F |
| Human, Mouse, Rat, Dog, Chicken, Rabbit |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic peptide derived from human alpha Adducin |
| 441-540/737 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 118 |
| Cytoplasm, Cell membrane |
| ADD 1; ADD A; ADD1; ADD1 protein; ADDA; ADDA_HUMAN; Adducin 1 alpha; Adducin 1 alpha; Alpha adducin; Alpha-adducin; Erythrocyte adducin alpha subunit; Erythrocyte adducin subunit alpha; MGC3339; MGC44427; OTTHUMP00000151163; OTTHUMP00000151164; OTTHUMP00000151165; OTTHUMP00000218664; OTTHUMP00000218665 |
| Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta and gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-Actin junction of the membrane skeleton. The cortical Actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical Actin network organization. Adducin alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin alpha and Adducin gamma is ubiquitous in contrast to the restricted expression of Adducin beta . Adducin beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow in humans and spleen in mice. |
| Application Dilution |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
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