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CDKN2A/p16INK4a Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Human
Overview
Catalog # bs-4592R-Biotin
Product Name CDKN2A/p16INK4a Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Specificity Targets p16INK4a
Reactivity Human
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human CDKN2A
Immunogen Range 31-100/156
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1029
Swiss Prot P42771
Subcellular location Nucleus
Synonyms Cyclin-dependent kinase inhibitor 2A; Cyclin-dependent kinase 4 inhibitor A; CDK4I; Multiple tumor suppressor 1; MTS-1; p16-INK4a; p16-INK4; p16INK4A; p12; CDKN2; MTS1.
Background Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500