Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) Protein
Applications
Reactivity
| Overview | |
| Catalog # | bs-46017P |
| Product Name | Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) Protein |
| Applications |
WB
ELISA
HPLC
|
| Reactivity | SARS-CoV-2 |
| Specifications | |
| Conjugation | Unconjugated |
| Source | Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) protein is expressed from mammalian with a His-tag at the C-terminal |
| Storage Buffer | Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization. |
| Storage Condition | The product should be stored at -70°C or -20°C. |
| Target | |
| Gene ID | YP_009724390.1 |
| Background | SARS-CoV-2 exploits angiotensin-converting enzyme 2 (ACE2) as a receptor to invade cells. It has been reported that the UK and South African strains may have higher transmission capabilities, eventually in part due to amino acid substitutions on the SARS-CoV-2 Spike protein. The results of a study show the N501Y replacement in this region of the interface (present in both the UK and South African strains) should be favorable for the interaction with ACE2, while the K417N and E484K substitutions (South African strain) would seem neutral or even unfavorable. |
Frequently asked questions
Which applications is Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) Protein (bs-46017P) validated for, and at what dilution?
bs-46017P is validated for WB, ELISA, HPLC.
Which species does Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) Protein (bs-46017P) react with?
Tested reactivity: SARS-CoV-2.
How should bs-46017P be stored?
The product should be stored at -70°C or -20°C. Storage buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.
How is Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) Protein (bs-46017P) produced?
Recombinant SARS-COV-2 Spike S1 (N501Y, K417N, E484K) protein is expressed from mammalian with a His-tag at the C-terminal