| Overview |
| bs-46110p-rbitc-100ug |
| Recombinant Human ACE2 Protein, RBITC Conjugated |
| WB |
| Human |
| Specifications |
| RBITC |
| Recombinant Human ACE2 Protein protein is expressed in Mammalian cells with C-His. It contains the amino acid sequence of Met1-Ser740. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| NP_001358344.1 |
| Q9BYF1 |
| Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family. The ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be highly expressed in testis, kidney, and heart, in the colon, small intestine, and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor, don’t inhibit ACE-2 activity. ACE-2 may play an essential role in regulating heart function. |
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