GRM2 Polyclonal Antibody

Applications

IHC-P
IF(IHC-P)

Reactivity

Human
Mouse
Rat

Predicted Reactivity

Dog
Cow
Horse
Chicken
Rabbit

Overview
Catalog #	bs-4769r
Product Name	GRM2 Polyclonal Antibody
Applications	IHC-P, IF(IHC-P)
Reactivity	Human, Mouse, Rat
Predicted Reactivity	Dog, Cow, Horse, Chicken, Rabbit
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human GRM2/GLUR2
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20C for 12 months.
Target
Gene ID	2912
Subcellular location	Extracellular
Synonyms	Glutamate Receptor Metabotropic 2; Gprc1b; AMPA selective glutamate receptor 2; GLUR 2; GLUR2; GLURB; Glutamate receptor metabotropic 2; Metabotropic Glutamate Receptor 2; GPRC1B; GRM 2; Grm2; mGlu 2; MGlu2; MGLUR 2; Mglur2; GRM2_HUMAN.
Background	L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Application Dilution
IHC-P
IF(IHC-P)