CD45 Polyclonal Antibody

Applications

  • FCM
  • IHC-P
  • IF(IHC-P)

Reactivity

  • Rat
Overview
Catalog # bs-4819R
Product Name CD45 Polyclonal Antibody
Applications FCM, IHC-P, IF(IHC-P)
Reactivity Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from rat CD45
Immunogen Range 520-570/1273
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
Target
Gene ID 24699
Swiss Prot P04157
Subcellular location Extracellular
Synonyms Lca; RT7; CD45; L-CA; T200; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; Ptprc
Background Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
Application Dilution
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200