Overview |
bs-4905R-FITC |
SORBS2 Polyclonal Antibody, FITC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat |
Dog, Pig, Horse, Chicken, Rabbit |
Specifications |
FITC |
Rabbit |
KLH conjugated synthetic peptide derived from human SORBS2/ArgBP2 |
401-500/664 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
8470 |
O94875 |
Cytoplasm |
ARGBP2; PRO618; Sorbin and SH3 domain-containing protein 2; Arg/Abl-interacting protein 2; Sorbin; SORBS2; KIAA777 |
Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |