ARP4 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • IHC-P

Reactivity

  • Mouse
  • Rat

Predicted Reactivity

  • Human
  • Dog
  • Cow
  • Pig
  • Rabbit
Overview
Catalog # bs-5027R
Product Name ARP4 Polyclonal Antibody
Applications WB, ELISA, IHC-P
Reactivity Mouse, Rat
Predicted Reactivity Human, Dog, Cow, Pig, Rabbit
Specifications
Conjugation Unconjugated
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse ARP4
Immunogen Range 331-410/410
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 57875
Swiss Prot Q9Z1P8
Subcellular location Secreted, Extracellular matrix
Synonyms Arp4; Bk89; Fiaf; Ng27; Pgar; Hfarp; Pgarg; Pp1158; Angiopoietin-related protein 4; 425O18-1; Angiopoietin-like protein 4; Fasting-induced adipose factor; Hepatic fibrinogen/angiopoietin-related protein; Secreted protein Bk89; Angptl4; Farp
Background Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400