| Overview |
| bs-51101R |
| WDR5 Polyclonal Antibody |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against human WDR5 (WD (tryptophan-aspartate) repeat domain 5), using a recombinant protein |
| Polyclonal |
| Not determined |
| 2ug/ul |
| Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300 |
| PBS with 0.05% sodium azide and 0.05% Proclin300. |
| Store at -20°C for 12 months. |
| Target |
| 11091 |
| P61964 |
| WD repeat-containing protein 5, WDR5, BMP2-induced 3-kb gene protein, BIG3 |
| Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation. |
| Application Dilution |
| WB |
1:300-5000 |
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