| Overview |
| bs-51123R |
| HP1 alpha Polyclonal Antibody |
| WB, IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against human HP1 alpha (Heterochromatin protein 1 homolog alpha), using the full length recombinant GST tagged protein |
| Polyclonal |
| Not determined |
| 2ug/ul |
| Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300 |
| PBS with 0.05% sodium azide and 0.05% Proclin300. |
| Store at -20°C for 12 months. |
| Target |
| 23468 |
| P45973 |
| Chromobox protein homolog 5, CBX5, Antigen p25, Heterochromatin protein 1 homolog alpha, HP1 alpha, HP1A |
| Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
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