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proBNP Polyclonal Antibody, Biotin Conjugated

Applications

  • ELISA
  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-5145R-Biotin
Product Name proBNP Polyclonal Antibody, Biotin Conjugated
Applications ELISA, IHC-P, IHC-F
Reactivity Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from mouse proBNP
Immunogen Range 21-121/121
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 18158
Subcellular location Secreted
Synonyms BNP 32; BNP1-28; BNP1-29; BNP1-30; BNP1-32; BNP2-31; BNP3-29; BNP3-30; BNP3-32; BNP4-27; BNP4-29; BNP4-30; BNP4-31; BNP4-32; BNP5-29; BNP5-31; BNP5-32; Brain natriuretic peptide 32; Brain type natriuretic peptide; Gamma brain natriuretic peptide; Natriuretic peptide B; Natriuretic peptide brain type; Natriuretic peptide precursor B; natriuretic peptide, brain type; ANFB_MOUSE; Natriuretic peptides B; natriuretic protein; NPPB; NPPB protein.
Background This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
Application Dilution
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500