proBNP Polyclonal Antibody, Cy5.5 Conjugated
Applications
Reactivity
| Overview | |
| Catalog # | bs-5145R-Cy5.5-100uL |
| Product Name | proBNP Polyclonal Antibody, Cy5.5 Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Mouse, Rat |
| Specifications | |
| Conjugation | Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from mouse proBNP |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 18158 |
| Subcellular location | Secreted |
| Synonyms | BNP 32; BNP1-28; BNP1-29; BNP1-30; BNP1-32; BNP2-31; BNP3-29; BNP3-30; BNP3-32; BNP4-27; BNP4-29; BNP4-30; BNP4-31; BNP4-32; BNP5-29; BNP5-31; BNP5-32; Brain natriuretic peptide 32; Brain type natriuretic peptide; Gamma brain natriuretic peptide; Natriuretic peptide B; Natriuretic peptide brain type; Natriuretic peptide precursor B; natriuretic peptide, brain type; ANFB_MOUSE; Natriuretic peptides B; natriuretic protein; NPPB; NPPB protein. |
| Background | This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. |
| Application Dilution | |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is proBNP Polyclonal Antibody, Cy5.5 Conjugated (BS-5145R-CY5-5) validated for, and at what dilution?
BS-5145R-CY5-5 is validated for IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does proBNP Polyclonal Antibody, Cy5.5 Conjugated (BS-5145R-CY5-5) react with?
Tested reactivity: Mouse, Rat.
How should BS-5145R-CY5-5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise proBNP Polyclonal Antibody, Cy5.5 Conjugated (BS-5145R-CY5-5)?
KLH conjugated synthetic peptide derived from mouse proBNP
What are the excitation and emission wavelengths of the Cy5.5 conjugate (BS-5145R-CY5-5)?
Cy5.5 on BS-5145R-CY5-5: excitation / emission 675nm/694nm.