phospho-BRIP1/BACH1 (Ser990) Polyclonal Antibody, PE-Cy5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-5226R-PE-Cy5 |
| Product Name | phospho-BRIP1/BACH1 (Ser990) Polyclonal Antibody, PE-Cy5 Conjugated |
| Applications |
WB
|
| Specificity | This phosphorylation site is homologous to that of Ser921 in Bovine. |
| Reactivity | Human, Mouse |
| Predicted Reactivity | Cow, Sheep |
| Specifications | |
| Conjugation | PE-Cy5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human BRIP1 around the phosphorylation site of Ser990 |
| Modification Site | Ser990 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 83990 |
| Swiss Prot | Q9BX63 |
| Subcellular location | Nucleus |
| Synonyms | OF; BACH1; FANCJ; Fanconi anemia group J protein; Protein FACJ; ATP-dependent RNA helicase BRIP1; BRCA1-associated C-terminal helicase 1; BRCA1-interacting protein C-terminal helicase 1; BRCA1-interacting protein 1; BRIP1 |
| Background | DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. |
| Application Dilution | |
| WB | 1:300-5000 |