Cdc25B (Ser353) Polyclonal Antibody
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-5245R |
Product Name | Cdc25B (Ser353) Polyclonal Antibody |
Applications | WB, ELISA, IHC-P |
Specificity | This phosphorylation site is homologous to that of Ser351 in Mouse and Ser 349 in Rat. |
Reactivity | Human, Mouse |
Predicted Reactivity | Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser353 |
Modification Site | Ser353 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 994 |
Swiss Prot | P30305 |
Subcellular location | Cytoplasm |
Synonyms | M-phase inducer phosphatase 2; Dual specificity phosphatase Cdc25B; CDC25B; CDC25HU2 |
Background | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. |
Application Dilution | |
WB | 1:300-5000 |
ELISA | 1:500-1000 |
IHC-P | 1:200-400 |