| Overview |
| bs-5245R-HRP |
| phospho-Cdc25B (Ser353) Polyclonal Antibody, HRP Conjugated |
| WB, ELISA, IHC-P |
| This phosphorylation site is homologous to that of Ser351 in Mouse and Ser 349 in Rat. |
| Mouse |
| Human, Rat |
| Specifications |
| HRP |
| Rabbit |
| KLH conjugated synthetic phosphopeptide derived from human Cdc25B around the phosphorylation site of Ser353 |
| Ser353 |
| Polyclonal |
| #REF! |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 994 |
| P30305 |
| Cytoplasm |
| M-phase inducer phosphatase 2; Dual specificity phosphatase Cdc25B; CDC25B; CDC25HU2 |
| Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity. |
| Application Dilution |
| WB |
1:300-5000 |
| ELISA |
1:500-1000 |
| IHC-P |
1:200-400 |