| Overview |
| bs-53086R |
| CDYL Polyclonal Antibody |
| ELISA |
| Human, Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| Polyclonal antibody raised in rabbit against human CDYL (chromodomain protein, Y-like) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein |
| Polyclonal |
| Not Determined |
| Not Determined |
| Whole antiserum from rabbit containing 0.05% azide |
| Serum with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 9425 |
| Q9Y232 |
| CDYL1, Chromodomain Y-like protein, CDYL |
| Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2); acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4. |
| Application Dilution |
| ELISA |
1:500-1000 |
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