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Ski3 Polyclonal Antibody

Applications

  • WB
  • IF(ICC)
  • IF

Reactivity

  • Human
Overview
Catalog # bs-53094R
Product Name Ski3 Polyclonal Antibody
Applications WB, IF(ICC), IF
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein
Clonality Polyclonal
Clone # #REF!
Isotype Not Determined
Concentration 3ug/ul
Purification Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 852659
Swiss Prot Q02793
Synonyms Antiviral protein SKI8, SKI8, Superkiller protein 8, REC103
Background Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200
IF