phospho-GABBR2 (Ser892) Polyclonal Antibody, Cy5.5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-5357R-Cy5.5-100uL |
| Product Name | phospho-GABBR2 (Ser892) Polyclonal Antibody, Cy5.5 Conjugated |
| Applications |
WB
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, Dog, Cow, Pig, Chicken |
| Specifications | |
| Conjugation | Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser892 |
| Modification Site | Ser892 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 9568 |
| Subcellular location | Cell membrane |
| Synonyms | GABA B Receptor 2 phospho S892; p-GABA B Receptor 2 phospho S892; p-GABBR2 Ser892; GABBR2; GB2; G protein coupled receptor 51; G-protein coupled receptor 51; GAB B R2; GABA B R2; GABA B receptor 2; GABA B RECEPTOR; GABA-B receptor 2; GABA-B-R2; GABA-BR2; GABA[[B]]R2; GABAB R2; GABABR 2; GABABR2; GABB R2; GABBR 2; Gabbr2; GABR2_HUMAN; Gamma aminobutyric acid GABA B receptor 2; Gamma aminobutyric acid B receptor 2; Gamma aminobutyric acid GABA B receptor 2; Gamma aminobutyric acid type B receptor subunit 2; Gamma-aminobutyric acid type B receptor subunit 2; Gb 2; Gb2; GH07312; GPR 51; GPR51; GPRC 3B; GPRC3B; HG 20; HG20; HRIHFB2099; Metabotropic GABA B receptor subtype 2; OTTHUMP00000021776; OTTHUMP00000063797; R2 SUBUNIT; BcDNA:GH07312; CG6706; CT20836; D GABA[[B]]R2; D Gaba2; FLJ36928. |
| Background | The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]. |
| Application Dilution | |
| WB | 1:300-5000 |
| IF(IHC-P) | 1:50-200 |
| IF(IHC-F) | 1:50-200 |
| IF(ICC) | 1:50-200 |
Frequently asked questions
Which applications is phospho-GABBR2 (Ser892) Polyclonal Antibody, Cy5.5 Conjugated (BS-5357R-CY5-5) validated for, and at what dilution?
BS-5357R-CY5-5 is validated for WB (1:300-5000); IF(IHC-P) (1:50-200); IF(IHC-F) (1:50-200); IF(ICC) (1:50-200). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does phospho-GABBR2 (Ser892) Polyclonal Antibody, Cy5.5 Conjugated (BS-5357R-CY5-5) react with?
Tested reactivity: Human. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Rat, Dog, Cow, Pig, Chicken.
How should BS-5357R-CY5-5 be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-GABBR2 (Ser892) Polyclonal Antibody, Cy5.5 Conjugated (BS-5357R-CY5-5)?
KLH conjugated synthetic phosphopeptide derived from human GABBR2 around the phosphorylation site of Ser892
What are the excitation and emission wavelengths of the Cy5.5 conjugate (BS-5357R-CY5-5)?
Cy5.5 on BS-5357R-CY5-5: excitation / emission 675nm/694nm.