PLCZ1 Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-5378R-PerCP |
| Product Name | PLCZ1 Polyclonal Antibody, PerCP Conjugated |
| Applications |
IF(IHC-P)
IF(IHC-F)
IF(ICC)
|
| Reactivity | Human, Rat |
| Predicted Reactivity | Mouse, Dog, Cow, Pig, Horse |
| Specifications | |
| Conjugation | PerCP |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human PLCZ1 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 89869 |
| Swiss Prot | Q86YW0 |
| Subcellular location | Cytoplasm, Nucleus |
| Synonyms | PLCzeta; NYD-SP27; PLC-zeta-1; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; Phosphoinositide phospholipase C-zeta-1; Phospholipase C-zeta-1; Testis-development protein NYD-SP27; PLCZ1; PLCZ1_HUMAN |
| Background | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function. |
| Application Dilution | |
| IF(IHC-P) | |
| IF(IHC-F) | |
| IF(ICC) | |
Frequently asked questions
Which applications is PLCZ1 Polyclonal Antibody, PerCP Conjugated (bs-5378R-PerCP) validated for, and at what dilution?
bs-5378R-PerCP is validated for IF(IHC-P), IF(IHC-F), IF(ICC).
Which species does PLCZ1 Polyclonal Antibody, PerCP Conjugated (bs-5378R-PerCP) react with?
Tested reactivity: Human, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Mouse, Dog, Cow, Pig, Horse.
How should bs-5378R-PerCP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise PLCZ1 Polyclonal Antibody, PerCP Conjugated (bs-5378R-PerCP)?
KLH conjugated synthetic peptide derived from human PLCZ1