phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, PerCP Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-5449R-PerCP-100uL |
| Product Name | phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, PerCP Conjugated |
| Applications |
FCM
|
| Reactivity | Mouse, Rat |
| Predicted Reactivity | Human, Dog, Cow, Pig, Chicken |
| Specifications | |
| Conjugation | PerCP |
| Host | Rabbit |
| Source | KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166 |
| Modification Site | Tyr1165 + Tyr1166 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 3480 |
| Swiss Prot | P08069 |
| Subcellular location | Cell membrane |
| Synonyms | IGF-1R Tyr1165/Tyr1166; IGF1R phospho Y1165+Y1166; IGF1R phospho Tyr1165+Tyr1166; p-IGF1R Tyr1165+Tyr1166; CD221; CD221 antigen; IGF 1 receptor; IGF 1R; IGF I receptor; IGF1R; IGFIR; IGFIRC; Insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; JTK13; MGC142170; MGC142172; IGF1 Receptor; IGF1R_HUMAN. |
| Background | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq, Jul 2008]. |
| Application Dilution | |
| FCM | 1:20-100 |
Frequently asked questions
Which applications is phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, PerCP Conjugated (bs-5449R-PerCP) validated for, and at what dilution?
bs-5449R-PerCP is validated for FCM (1:20-100). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, PerCP Conjugated (bs-5449R-PerCP) react with?
Tested reactivity: Mouse, Rat. Predicted reactivity (expected from sequence homology but not yet tested): Human, Dog, Cow, Pig, Chicken.
How should bs-5449R-PerCP be stored?
Store at -20C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. Storage buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise phospho-IGF1R (Tyr1165 + Tyr1166) Polyclonal Antibody, PerCP Conjugated (bs-5449R-PerCP)?
KLH conjugated synthetic phosphopeptide derived from human IGF1R around the phosphorylation site of Tyr1165+Tyr1166
What are the excitation and emission wavelengths of the PerCP conjugate (bs-5449R-PerCP)?
PerCP on bs-5449R-PerCP: excitation / emission 482nm/677nm.