ADRBK1 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-55002R |
| Product Name | ADRBK1 Polyclonal Antibody |
| Applications |
WB
IHC
IHC-P
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2). |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | Lot Dependent |
| Purification | purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C for 12 months. |
| Target | |
| Gene ID | 156 |
| Swiss Prot | P25098 |
| Subcellular location | Cytoplasm |
| Synonyms | GRK2;ADRBK1;BARK1;BETA-ARK1 |
| Background | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | 1:50-200 |
| IHC-P | 1:200-400 |
Frequently asked questions
Which applications is ADRBK1 Polyclonal Antibody (bs-55002R) validated for, and at what dilution?
bs-55002R is validated for WB (1:300-5000); IHC (1:50-200); IHC-P (1:200-400). These are recommended starting dilutions; optimal dilutions should be determined by the end user.
Which species does ADRBK1 Polyclonal Antibody (bs-55002R) react with?
Tested reactivity: Human, Mouse, Rat.
How should bs-55002R be stored?
Store at -20°C for 12 months. Storage buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
What immunogen was used to raise ADRBK1 Polyclonal Antibody (bs-55002R)?
Recombinant fusion protein containing a sequence corresponding to amino acids 440-689 of human ADRBK1 (NP_001610.2).
