BAK1 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-55017R |
| Product Name | BAK1 Polyclonal Antibody |
| Applications | WB, IHC |
| Reactivity | Human, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | A synthetic peptide of human BAK1 |
| Clonality | Polyclonal |
| Clone # | #REF! |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 578 |
| Swiss Prot | Q16611 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | BAK1;BAK;BAK-LIKE;BCL2L7 |
| Background | The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | |
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