Beclin 1 Polyclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-55024R
Product Name Beclin 1 Polyclonal Antibody
Applications WB, IHC-P, IF(ICC)
Specificity KO-Validated
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Beclin 1 (NP_003757.1).
Immunogen Range 181-280/450
Clonality Polyclonal
Isotype IgG
Concentration 0.5ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID 8678
Swiss Prot Q14457
Subcellular location Cytoplasm, Cell membrane
Synonyms ATG6;VPS30;beclin1;Beclin 1;BECN1;beclin-1
Background This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200