Beclin 1 Polyclonal Antibody, PerCP-Cy5.5 Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-55024r-percp-cy55-100ul |
| Product Name | Beclin 1 Polyclonal Antibody, PerCP-Cy5.5 Conjugated |
| Applications |
WB
IF
|
| Specificity | KO-Validated |
| Reactivity | Human, Mouse, Rat |
| Predicted Reactivity | Rabbit |
| Specifications | |
| Conjugation | PerCP-Cy5.5 |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human BECN1 |
| Immunogen Range | 181-280/450 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1mg/ml |
| Purification | purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target | |
| Gene ID | 8678 |
| Swiss Prot | Q14457 |
| Subcellular location | Cytoplasm, Cell membrane |
| Synonyms | ATG6; VPS30; beclin1; BECN1_HUMAN; BECN1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197; GT197; BECN1_MOUSE; BECN1_RAT; beclin 1; beclin 1 (coiled-coil, moesin-like BCL2 interacting protein); beclin 1, autophagy related; ATG6 autophagy related 6 homolog (S. cerevisiae) |
| Background | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. |
| Application Dilution | |
| WB | 1:500-1000 |
| IF | 1:100-500 |