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DPYSL2 Polyclonal Antibody

Applications

  • WB

Reactivity

  • Human
Overview
Catalog # bs-55057R
Product Name DPYSL2 Polyclonal Antibody
Applications WB
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source A synthetic peptide corresponding to a sequence within amino acids 400-500 of human DPYSL2 (NP_001377.1).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 1808
Swiss Prot Q16555
Subcellular location Cytoplasm
Synonyms DPYSL2;CRMP-2;CRMP2;DHPRP2;DRP-2;DRP2;N2A3;ULIP-2;ULIP2
Background This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Application Dilution
WB 1:300-5000