HDAC1 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • FCM
  • IHC-P
  • IHC-F
  • IP
  • IF

Reactivity

  • Human

Predicted Reactivity

  • Mouse
  • Rat
Overview
Catalog # bs-55093R
Product Name HDAC1 Polyclonal Antibody
Applications WB, ELISA, FCM, IHC-P, IHC-F, IP, IF
Specificity KO-Validated
Reactivity Human
Predicted Reactivity Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 393-482 of human HDAC1 (NP_004955.2).
Immunogen Range 393-482/482
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 3065
Swiss Prot Q13547
Subcellular location Nucleus
Synonyms GON-10;HD1;RPD3;RPD3L1;HDAC1
Background Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Application Dilution
WB 1:300-1000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IP 1-2ug
IF