Overview |
bs-55094R |
HDAC8 Polyclonal Antibody |
WB, IHC-P, IHC, IF |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human HDAC8 (NP_060956.1). |
1-377/377 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
55869 |
Q9BY41 |
Cytoplasm, Nucleus |
HDAC8;CDA07;CDLS5;HD8;HDACL1;MRXS6;RPD3;WTS |
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IHC |
|
IF |
|