| Overview |
| bs-55153R |
| NFKB2 Polyclonal Antibody |
| WB, IHC, IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| Recombinant fusion protein containing a sequence corresponding to amino acids 690-899 of human NFKB2 (NP_002493.3). |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 4791 |
| Q00653 |
| Cytoplasm, Nucleus |
| CVID10;H2TF1;LYT-10;LYT10;NF-kB2;p100;p49/p100;p52 |
| This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC |
|
| IF |
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