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PRDX2 Polyclonal Antibody

Applications

  • WB
  • IF(ICC)
  • IF

Reactivity

  • Human
  • Mouse
Overview
Catalog # bs-55172R
Product Name PRDX2 Polyclonal Antibody
Applications WB, IF(ICC), IF
Reactivity Human, Mouse
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-142 of human PRDX2 (NP_859428.1).
Clonality Polyclonal
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 7001
Swiss Prot P32119
Subcellular location Cytoplasm
Synonyms PRDX2;HEL-S-2a;NKEF-B;NKEFB;PRP;PRX2;PRXII;PTX1;TDPX1;TPX1;TSA
Background This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200
IF