PSIP1 Polyclonal Antibody

$Lane 1: 293T cell lysates; Lane 2: PSIP1 knockout (KO) 293T cell lysates probed with PSIP1 Polyclonal Antibody, Unconjugated (bs-55178R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.$

Lane 1: 293T cell lysates; Lane 2: PSIP1 knockout (KO) 293T cell lysates probed with PSIP1 Polyclonal Antibody, Unconjugated (bs-55178R) at 1:1000 dilution and 4\u02daC overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37\u02daC.

Applications

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bs-55178R
Product Name	PSIP1 Polyclonal Antibody
Applications	WB
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	11168
Swiss Prot	O75475
Subcellular location	Nucleus
Synonyms	PSIP1;DFS70;LEDGF;PAIP;PSIP2;p52;p75
Background	Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
Application Dilution
WB	1:300-5000